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KMID : 1149120200170020047
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Journal of the Korean Society for Psoriasis
2020 Volume.17 No. 2 p.47 ~ p.49
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A Case of Psoriasis During Abatacept Treatment in a Patient with Rheumatoid Arthritis
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Lee Su-Min
Ko Byeong-Chang
Park Hai-Jin
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Abstract
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Abataceptis a fully human soluble costimulation modulator that selectively targets the CD80,CD86-CD28 co-signaling pathway required for T cell activation. A 66-year-old woman with a history of rheumatoid arthritis for 20 years presented with scaly erythematous patches and plaques on her whole bodysince 4 months ago. She has been treated with abatacept for rheumatoid arthritis during the last 5 years and had no previous history of psoriasis. The patient was diagnosed with psoriasis, she was treatedwith NBUVB, topical ointment, and oral acitretinfor 3 months but, her skin lesionswerewaxed and waned.After abatacept was discontinued,her psoriatic skin lesion was improved with oral cyclosporin. Herein, we report a rare case of psoriasis during abatacept treatment.
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KEYWORD
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Abatacept, Psoriasis, Rheumatoid arthritis
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